New syntheses of (±)-tashiromine and (±)-epitashiromine via enaminone intermediates
نویسندگان
چکیده
The syntheses of the naturally occurring indolizidine alkaloid (±)-tashiromine and its unnatural epimer (±)-epitashiromine are demonstrated through the use of enaminone chemistry. The impact of various electron-withdrawing substituents at the C-8 position of the indolizidine core on the preparation of the bicyclic system is described.
منابع مشابه
Novel stereocontrolled syntheses of tashiromine and epitashiromine
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